Information

The following are all in PDF format. Click on the link to open.

• Technology Notes
  • An introduction to Biacore's SPR technology
  • Surface Plasmon Resonance
  • Recovering samples from Biacore® 3000 for mass spectrometry
• Application Notes
  • Characterization of monoclonal antibody epitope specificity using Biacore's SPR technology
  • Comparison of a structural and functional binding domain in human growth hormone
  • Multicomponent analysis: formation of a quarternary signal transduction complex
  • The study of interactions between lectins and immobilized glycoproteins using Biacore's SPR technology
  • Observing DNA at work with Biacore's SPR technology
  • Ligand Fishing with Biacore® 3000--Selective binding, recovery and identification by MALDI MS of a specific interaction partner
  • Ligand immobilization using thiol-disulphide exchange
• Scientific Reviews
  • Ligand fishing with Biacore®
  • Accelerating ligand identification
  • Proteomics: life's rich tapestry is now on show
  • Biacore and mass spectrometry: more than just a marriage of convenience
  • BIA-MS: identification of epitope-tagged peptides present in E.coli lysates
  • From monofunctional to bifunctional inhibitors
  • Substrate specificity of DNA repair enzymes
  • Biacore analysis of rationally designed anti-HER2 exocyclic mimetics of antibodies
  • The proto-oncogene Ras
  • Biacore's SPR technology as a mutation screening tool
  • The L1 Chip
  • Driving towards new anti-cancer drugs
  • Growing impact of Biacore on drug discovery
  • Stay on track in drug discovery